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Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται -> For extreme diseases, extreme methods of cure, as to restriction, are most suitable.
Corpus Hippocraticum, Aphorisms 1.6.2