צָרַר
From LSJ
Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → But for extreme illnesses, extreme remedies, applied with severe exactitude, are the best (Hippocrates, Aphorism 6)
English (Strong)
a primitive root; to cramp, literally or figuratively, transitive or intransitive (as follows): adversary, (be in) afflict(-ion), beseige, bind (up), (be in, bring) distress, enemy, narrower, oppress, pangs, shut up, be in a strait (trouble), vex.