irrevocably

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ἔκστασίς τίς ἐστιν ἐν τῇ γενέσει τὸ παρὰ φύσιν τοῦ κατὰ φύσιν → what is contrary to nature is any developmental aberration from what is in accord with nature (Aristotle, On the Heavens 286a19)

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