οὐκ ἔστι λύπης ἄλγημα μεῖζον → there is no greater pain than grief
nĕfārĭē: adv., v. nefarius.
nĕfārĭē¹¹ (nefarius), d’une manière impie, abominable, criminellement : Cic. Verr. 2, 2, 117 ; Mil. 67 ; Cat. 2, 1.