ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → for extreme diseases, extreme methods of cure, as to restriction, are most suitable (Corpus Hippocraticum, Aphorisms 1.6.2)
P. τραχέως, σχετλίως, P. and V. πικρῶς, Ar. and P. χαλεπῶς, P. σκληρῶς.
act harshly towards: P. ἀγνωμονεῖν πρός (acc.).