To χάρις ὑμῖν οὕτω τίθησιν κτλ. → Thus he writes joy to you all, etc. (Cramer's Catena on 1 Thessalonians 1.1)
ἀπόλωλα: Μέσ. παρακ. του ἀπόλλυμι.
it is all over with me, my doom is sealed