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Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται -> For extreme diseases, extreme methods of cure, as to restriction, are most suitable.
Corpus Hippocraticum, Aphorisms 1.6.2

Latin > English (Lewis & Short)

I adv. comp., and dĭūtissĭme, adv. sup., v. diu.

Latin > French (Gaffiot)

dĭūtĭus, dĭūtissĭmē, v. diu.

Latin > German (Georges)

diūtius, diūtissimē, s.2. diū.