gravamen
From LSJ
τὸν ἰητρὸν δοκέει μοι ἄριστον εἶναι πρόνοιαν ἐπιτηδεύειν → it appears to me a most excellent thing for the physician to cultivate prognosis
Latin > English (Lewis & Short)
grăvāmen: ĭnis, n. id.,
I trouble, physical inconvenience (late Lat.), Cassiod. Varr. 9, 2; Cod. Just. 5, 30, 5.
Latin > French (Gaffiot 2016)
grăvāmĕn, ĭnis (-entum, ī, Gloss.), n. (gravo), incommodité : Cassiod. Var. 9, 2.