detrimentosus

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Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → But for extreme illnesses, extreme remedies, applied with severe exactitude, are the best (Hippocrates, Aphorism 6)

Source

Latin > English (Lewis & Short)

dētrīmentōsus: a, um, adj. detrimentum,
I hurtful, detrimental: ab hoste discedere detrimentosum esse existimabat, Caes. B. G. 7, 33.