Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → For extreme diseases, extreme methods of cure, as to restriction, are most suitable.
(see also: ὀχμάζω) bridle a horse, hold fast, make fast