pernecesse
From LSJ
ἀσκέειν, περὶ τὰ νουσήματα, δύο, ὠφελέειν, ἢ μὴ βλάπτειν → strive, with regard to diseases, for two things — to do good, or to do no harm | as to diseases, make a habit of two things — to help, or at least, to do no harm
Latin > English (Lewis & Short)
per-nĕcesse:
I adj. indecl., very necessary, indispensably necessary: cum pernecesse esset, Cic. Tull. 21, 49.
Latin > German (Georges)
per-necesse, Adv., unumgänglich notwendig, esse, Cic. pro Tull. 49.