πικρότης
From LSJ
Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → For extreme diseases, extreme methods of cure, as to restriction, are most suitable.
English (LSJ)
ητος, ἡ,
A pungency, of taste, bitterness, Hp.Acut.23, VM 19, Pl.Tht.159e, Ti.83b : in pl., ib.82e. II metaph., bitterness, harshness, cruelty, τὴν [Ἀστυάγεος] π. Hdt.1.130 ; γλώσσῃ π. ἔνεστί τις E.El.1014 : pl., αἱ τῶν συκοφαντῶν π. Isoc.15.300.