perincommodus
From LSJ
Ζῆν οὐκ ἄξιος, ὅτῳ μηδὲ εἷς ἐστι χρηστὸς φίλος → Life is not worth living if you do not have at least one friend.
Latin > English (Lewis & Short)
pĕr-incommŏdus: a, um, adj.,
I very inconvenient, very troublesome or annoying: alicui, Liv. 37, 41, 3.—Adv.: pĕrin-commŏdē, very inconveniently, very unfortunately: accidit perincommode, quod, etc., Cic. Att. 1, 17, 2.