affliction
From LSJ
anything that causes trouble: P. and V. κακόν, τό, V. πῆμα, τό.
distress: P. and V. λύπη, ἡ, πόνος, ὁ, V. πῆμα, τό, πημονή, ἡ, πένθος, τό, P. ταλαιπωρία, ἡ.
misfortune: P. and V. δυσπραξία, ἡ, συμφορά, ἡ, πάθος, το, πάθημα, τό, P. δυστυχία, ἡ; see misfortune.
disease: P. and V. νόσος, ἡ, νόσημα, τό.