affliction
From LSJ
subs.
Anything that causes trouble: P. and V. κακόν, τό, V. πῆμα, τό.
Distress: P. and V. λύπη, ἡ, πόνος, ὁ, V. πῆμα, τό, πημονή, ἡ, πένθος, τό, P. ταλαιπωρία, ἡ.
Misfortune: P. and V. δυσπραξία, ἡ, συμφορά, ἡ, παθος, το, πάθημα, τό, P. δυστυχία, ἡ; see misfortune.
Disease: P. and V. νόσος, ἡ, νόσημα, τό.