Ἐς δὲ τὰ ἔσχατα νουσήματα αἱ ἔσχαται θεραπεῖαι ἐς ἀκριβείην, κράτισται → For extreme diseases, extreme methods of cure, as to restriction, are most suitable.
P. and V. πικρός, Ar. and P. δριμύς, στρυφνός, P. ὀξύς, αὐστηρός.
Met., P. and V. πικρός, P. αὐστηρός.